Collect. Czech. Chem. Commun. 1958, 23, 932-939
https://doi.org/10.1135/cccc19580932

Synthetische Analgetica II. Darstellung und Reaktionen einiger hydrierter Derivate des 1-Phenylisochinolins

V. Mychajlyszyn and J. O. Jílek

Individual author index pages


Other CCCC articles of these authors

  • I. Červená, J. O. Jílek, A. Dlabač and M. Protiva
    Potential depot neuroleptics in the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series; Esters of noroxyclothepin and related amino alcohols with unsaturated, branched-chain aliphatic, alicyclic, araliphatic and dicarboxylic acids
    1976, Vol. 41, Issue 11, pp. 3437–3451 [Abstract]
  • R. Smrž, J. O. Jílek, B. Kakáč, J. Holubek, E. Svátek, M. Bartošová and M. Protiva
    2(8)-Chloro-10(11)-(dimethylaminoalkyl)dibenzo[b,f]thiepins as potential CNS agents; Synthesis and pharmacological screening
    1976, Vol. 41, Issue 11, pp. 3420–3436 [Abstract]
  • R. Smrž, J. O. Jílek, K. Šindelář, B. Kakáč, E. Svátek, J. Holubek, J. Grimová and M. Protiva
    5(or 4)-Arylthio-2-methylthiopyrimidines as potential intermediates in the synthesis of tricyclic pyrimido systems
    1976, Vol. 41, Issue 9, pp. 2771–2787 [Abstract]
  • K. Šindelář, J. O. Jílek, V. Bártl, J. Metyšová, B. Kakáč, J. Holubek, E. Svátek, J. Pomykáček and M. Protiva
    Neuroleptics of the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series and related substances: Piperazine-alkylated homologues of octoclothepin and methiothepin, 5,5-dimethyl-10,11-dihydro-5H-dibenzo[b,f]silepin analogue of perathiepin
    1976, Vol. 41, Issue 3, pp. 910–922 [Abstract]
  • J. O. Jílek, I. Červená, Z. Kopicová, K. Šindelář, E. Svátek, J. Metyšová, A. Dlabač, J. Pomykáček and M. Protiva
    Potent neuroleptic agents: Some new amino alcohols of the 10-piperazinodibenzo[b,f]thiepin series and their derivatives
    1976, Vol. 41, Issue 2, pp. 443–458 [Abstract]
  • J. O. Jílek, J. Metyšová, J. Němec, Z. Šedivý, J. Pomykáček and M. Protiva
    Potential neuroleptics; N-aralkyl, N-(aroylalkyl) and N-pyridyl derivatives of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1975, Vol. 40, Issue 11, pp. 3386–3398 [Abstract]
  • J. O. Jílek, K. Šindelář, M. Rajšner, A. Dlabač, J. Metyšová, Z. Votava, J. Pomykáček and M. Protiva
    Noncataleptic potential neuroleptics; 2-Halogeno-10-piperazinodibenzo[b,f]thiepins
    1975, Vol. 40, Issue 9, pp. 2887–2904 [Abstract]
  • K. Šindelář, J. O. Jílek, J. Metyšová, J. Pomykáček and M. Protiva
    Potential metabolites of clorotepin: 2- and 3-hydroxy derivatives of 8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and their methyl ethers
    1974, Vol. 39, Issue 12, pp. 3548–3559 [Abstract]
  • J. O. Jílek, J. Metyšová, J. Pomykáček and M. Protiva
    8-Alkylthio-10-piperazinodibenzo[b,f]thiepins
    1974, Vol. 39, Issue 11, pp. 3338–3351 [Abstract]
  • J. O. Jílek, J. Metyšová and M. Protiva
    Cyclic acetals of the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series
    1974, Vol. 39, Issue 11, pp. 3153–3156 [Abstract]
  • K. Šindelář, J. Metyšová, B. Kakáč, J. Holubek, E. Svátek, J. O. Jílek, J. Pomykáček and M. Protiva
    8-Acyl derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1974, Vol. 39, Issue 8, pp. 2099–2114 [Abstract]
  • K. Šindelář, M. Rajšner, I. Červená, V. Valenta, J. O. Jílek, K. Kakáč, J. Holubek, E. Svátek, F. Mikšík and M. Protiva
    Neurotropic and psychotropic agents. LXVII. 1-[4,4-Bis(4-fluorophenyl)butyl]-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine and related compounds: New synthetic approaches
    1973, Vol. 38, Issue 12, pp. 3879–3901 [Abstract]
  • J. O. Jílek, K. Šindelář, A. Dlabač, E. Kazdová, J. Pomykáček, Z. Šedivý and M. Protiva
    Neurotropic and psychotropic agents. LVII. Esters of alcohols of the 10-piperazinodibenzo[b,f]thiepin series and of their analogues with fatty acids
    1973, Vol. 38, Issue 4, pp. 1190–1199 [Abstract]
  • J. O. Jílek, J. Metyšová, E. Svátek, F. Jančik, J. Pomykáček and M. Protiva
    Neurotropic and psychotropic agents. LVI. Sulfoxides, N-oxides and sulfones derived from neuroleptic 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1973, Vol. 38, Issue 2, pp. 599–610 [Abstract]
  • J. O. Jílek, K. Šindelář, J. Pomykáček, O. Horešovský, K. Pelz, E. Svátek, B. Kakáč, J. Holubek, J. Metyšová and M. Protiva
    Neurotropic and psychotropic compounds. LV. New syntheses of 8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and related compounds
    1973, Vol. 38, Issue 1, pp. 115–131 [Abstract]
  • J. O. Jílek, J. Metyšová and M. Protiva
    Neurotropic and psychotropic substances. XLIX. 3,8-Diazabicyclo[3.2.1]octyl derivatives of dibenzo[b,f]thiepin
    1971, Vol. 36, Issue 12, pp. 4074–4078 [Abstract]
  • J. O. Jílek, V. Seidlová, K. Pelz, B. Kakáč, J. Holubek, E. Svátek, Z. Šedivý and M. Protiva
    Neurotropic and psychotropic compounds. XLVIII. Several derivatives of phenanthrene, acenaphthene; anthracene and naphthalene
    1971, Vol. 36, Issue 9, pp. 3300–3313 [Abstract]
  • J. O. Jílek, J. Holubek, J. Pomykáček and M. Protiva
    Neurotropic and psychotropic compounds. XLVI. Several derivatives of cyclohexylphenyl sulfide
    1971, Vol. 36, Issue 8, pp. 2824–2830 [Abstract]
  • J. O. Jílek, J. Pomykáček, J. Metyšová and M. Protiva
    Neurotropic and psychotropic substances. XLV. Further 8-substituted 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins and related compounds. The nor-analogue of octoclothepin and its N-substitution derivatives
    1971, Vol. 36, Issue 6, pp. 2226–2247 [Abstract]
  • V. Seidlová, L. Novák, J. O. Jílek, J. Metyš and M. Protiva
    Antihistamine substances. LIII. ortho-Substituted derivatives of 1,1-diphenyl-1-(2-dimethylaminoethoxy)ethane
    1971, Vol. 36, Issue 1, pp. 299–303 [Abstract]
  • J. O. Jílek, K. Šindelář, J. Metyšová, J. Metyš, J. Pomykáček and M. Protiva
    Neurotropic and psychotropic substances. XLIV. 10-(Aminoalkoxy) and 10-piperazino derivatives of dibenzo[b,f]thiepin and related systems
    1970, Vol. 35, Issue 12, pp. 3721–3732 [Abstract]
  • J. O. Jílek, J. Pomykáček, J. Metyšová and M. Protiva
    Neurotropic and psychotropic compounds. XLI. 8-Cyano-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and related compounds
    1970, Vol. 35, Issue 1, pp. 276–283 [Abstract]
  • K. Pelz, M. Rajšner, J. O. Jílek and M. Protiva
    Neurotropic and psychotropic substances. XXVI. Derivatives of indole, benz[c,d]indole, benzimidazole and 3-benzazepine
    1968, Vol. 33, Issue 7, pp. 2111–2120 [Abstract]
  • J. O. Jílek, J. Metyšová, J. Pomykáček and M. Protiva
    Neurotrope und psychotrope Substanzen XIX. 8-Halogenderivate von 10-(4-Methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin und verwandte Substanzen
    1968, Vol. 33, Issue 6, pp. 1831–1845 [Abstract]
  • J. O. Jílek, E. Svátek, J. Metyšová, J. Pomykáček and M. Protiva
    Neurotrope und psychotrope Substanzen XVII. 10-(4-Methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin und einige Analoga
    1967, Vol. 32, Issue 9, pp. 3186–3212 [Abstract]
  • J. O. Jílek, J. Pomykáček and M. Protiva
    Synthetische Analgetika VII. 1-(2-Phenyl-2-aminoäthyl)-4-äthoxycarbonyl-4-phenylpiperidine
    1967, Vol. 32, Issue 3, pp. 1285–1288 [Abstract]
  • J. O. Jílek, K. Pelz, Z. J. Vejdělek and M. Protiva
    Neurotrope und psychotrope Substanzen VII. 2-Alkoxy-9-(3-dimethylaminopropyliden)thioxanthene und weitere Derivate von Prothixen
    1966, Vol. 31, Issue 1, pp. 269–278 [Abstract]
  • I. Ernest, J. O. Jílek, J. Jirkovský and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide XXXVI. Synthese des (±)-17-Desmethoxydeserpidins und (±)-17-Desmethoxy-3-isodeserpidins
    1965, Vol. 30, Issue 7, pp. 2395–2402 [Abstract]
  • K. Mori, D. M. S. Wheeler, J. O. Jílek, B. Kakáč and M. Protiva
    Synthetic experiments in the group of hypotensive alkaloids. XXXV. Microbiological reduction of the lactone of (±)-5-oxo-8β-hydroxy-cis-1,4,5,8,9,10-hexahydro-1β-naphthoic acid
    1965, Vol. 30, Issue 7, pp. 2236–2240 [Abstract]
  • J. O. Jílek, K. Pelz, D. Pavlíčková and M. Protiva
    Neurotrope und psychotrope Substanzen IV. Über einige neue Derivate des Dibenzo(b,f)(1,4)thiazepins
    1965, Vol. 30, Issue 5, pp. 1676–1683 [Abstract]
  • J. O. Jílek, J. Pomykáček, J. Metyšová, J. Metyš and M. Protiva
    Neurotrope und psychotrope Substanzen III. Derivate des Dibenz(b,f)(1,4)oxazepins
    1965, Vol. 30, Issue 2, pp. 463–471 [Abstract]
  • J. O. Jílek, J. Pomykáček, E. Svátek, V. Seidlová, M. Rajšner, K. Pelz, B. Hoch and M. Protiva
    Neurotrope und psychotrope Substanzen II. Morphanthridin und Derivate. Neue Synthese des Propazepins
    1965, Vol. 30, Issue 2, pp. 445–462 [Abstract]
  • M. Protiva, J. O. Jílek, J. Pomykáček, J. Jirkovský and Z. J. Vejdělek
    Synthetische Analgetica V. Synthetische Versuche auf Basis von 4-Phenyl-4-carbäthoxypiperidin (Norpethidin)
    1963, Vol. 28, Issue 10, pp. 2627–2636 [Abstract]
  • I. Ernest, J. O. Jílek, Z. J. Vejdělek and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide XXVI. Über einige neue (-)-Methylreserpat-Ester
    1963, Vol. 28, Issue 4, pp. 1022–1030 [Abstract]
  • J. O. Jílek, B. Kakáč and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide XIX. Reduktion des (±)-5,8-Dioxo-cis-1,4,5,8,9,10-hexahydro-1β-naphthoesäureisopropylesters nach Meerwein
    1961, Vol. 26, Issue 9, pp. 2229–2237 [Abstract]
  • M. Protiva, A. Čapek, J. O. Jílek, B. Kakáč and M. Tadra
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide XVIII. Mikrobiologische Reduktion des (±)-5-Oxo-8β-hydroxy-cis-1,4,5,8,9,10-hexahydro-1β-naphthoesäurelactons
    1961, Vol. 26, Issue 6, pp. 1537–1541 [Abstract]
  • J. O. Jílek, J. Pomykáček and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamen Alkaloide XV. Synthese racemischer Homoveratrylamin-Analoga des Reserpins und Isoreserpins
    1961, Vol. 26, Issue 4, pp. 1145–1159 [Abstract]
  • J. O. Jílek, I. Ernest, L. Novák, M. Rajšner and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide XII. Ein Beitrag zu den Endphasen der Totalsynthese von Reserpin und Deserpidin
    1961, Vol. 26, Issue 3, pp. 687–700 [Abstract]
  • L. Novák, J. O. Jílek, B. Kakáč, I. Ernest and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiver Alkaloide IX. Eine neue Methode der Racematspaltung bei der Reserpin-Totalsynthese
    1960, Vol. 25, Issue 8, pp. 2196–2206 [Abstract]
  • E. Adlerová, I. Ernest, V. Hněvsová, J. O. Jílek, L. Novák, J. Pomykáček, M. Rajšner, J. Sova, Z. J. Vejdělek and M. Protiva
    Synthetische Versuche in der Gruppe hypotensiv wirksamer Alkaloide VIII. Synthese einiger in Stellung 5, 6 und 7 substituierter Tryptaminderivate
    1960, Vol. 25, Issue 3, pp. 784–796 [Abstract]
  • E. Adlerová, L. Bláha, M. Borovička, I. Ernest, J. O. Jílek, B. Kakáč, L. Novák, M. Rajšner and M. Protiva
    Synthetische Versuche in der Gruppe der hypotensiv wirksamen Alkaloide VI. Einige Bemerkungen zur Darstellung der alicyclischen Komponente bei der Synthese von Verbindungen des Reserpin-Typus
    1960, Vol. 25, Issue 1, pp. 221–236 [Abstract]
  • J. O. Jílek and M. Protiva
    Synthetische Versuche in der Gruppe der östrogenen Hormone XIX. Über die Wagner-Meerweinsche Umlagerung von 1-Methyl-2-äthylcyclohexylcarbinol und deren Analogie in der Octahydrophenanthrenreihe
    1960, Vol. 25, Issue 1, pp. 165–179 [Abstract]
  • M. Protiva, Z. J. Vejdělek, J. O. Jílek and K. Macek
    Synthetische Modelle hypotensiv wirksamer Alkaloide V. Einige weitere Derivate des Tryptamins und 1,2,3,4-Tetrahydronorharmans
    1959, Vol. 24, Issue 12, pp. 3978–3987 [Abstract]
  • V. Mychajlyszyn and M. Protiva
    Antihistamin-Substanzen XLVI. Derivate des 2,3;6,7-Dibenzosuberans
    1959, Vol. 24, Issue 12, pp. 3955–3965 [Abstract]
  • M. Protiva, J. O. Jílek, V. Hach, E. Adlerová and V. Mychajlyszyn
    Synthetische Modelle hypotensiv wirksamer Alkaloide II. Einfache Reserpinmodelle mit dem Cyclohexanring E
    1959, Vol. 24, Issue 1, pp. 83–92 [Abstract]
  • M. Protiva, J. O. Jílek, E. Hachová, L. Novák, Z. J. Vejdělek and E. Adlerová
    Synthetische Modelle hypotensiv wirksamer Alkaloide I. 1-Aralkyl-1,2,3,4-tetrahydronorharmane
    1959, Vol. 24, Issue 1, pp. 74–82 [Abstract]
  • J. O. Jílek and M. Protiva
    Synthetische Versuche in der Gruppe der östrogenen Hormone XV. Über die Reaktion der Phenylacetylene mit substituiertes Cyclohexanonen. Neue Totalsynthese einer racemischen Doisynolsäure
    1958, Vol. 23, Issue 4, pp. 692–703 [Abstract]
  • V. Mychajlyszyn, J. O. Jílek and M. Protiva
    Synthetische Spasmolytica XIII. Basische Cyclohexyldiphenylcarbinole
    1957, Vol. 22, Issue 3, pp. 799–805 [Abstract]
  • V. Mychajlyszyn and J. O. Jílek
    Synthetische Spasmolytica XII. Derivate des α,α-Diphenyl-γ-methylmercaptobutyronitrils
    1957, Vol. 22, Issue 3, pp. 793–798 [Abstract]
  • M. Protiva, J. O. Jílek, L. Novák, E. Adlerová, V. Šimák and E. Knobloch
    Synthetische Versuche in der Gruppe der östrogenen Hormone VIII. Über die Chemie der Derivate des 2-Methyl-2-carboxy-6-oxycyclohexanons
    1956, Vol. 21, Issue 1, pp. 159–180 [Abstract]
  • J. O. Jílek and M. Protiva
    Synthetische Versuche in der Gruppe der östrogenen Hormone VII. Der kristalline Methylester der 2-Methyl-2-carbomethoxy-5-(4-methoxyphenyl)-cyclohexanon-6-essigsäure und Cyclisierungsversuche mit den Stereoisomeren 2-Methyl-5-(4-methoxyphenyl)-cyclohexanon-6-essigsäuren
    1955, Vol. 20, Issue 4, pp. 765–776 [Abstract]
  • M. Borovička, Z. Šedivý, J. O. Jílek and M. Protiva
    Sympatische Ganglien blockierende Stoffe III. Vom 2-(p-Aminophenyl)-äthylamin und 2-(p-Aminophenyl)-propylamin abgeleitete quartäre Salze
    1955, Vol. 20, Issue 2, pp. 437–451 [Abstract]
  • M. Protiva, J. O. Jílek, O. Exner, M. Borovička, J. Pliml, V. Šimák and Z. Šedivý
    Antihistamine substances. XXXI. On the mechanism of antihistamine action; Some simple benzylammonium and benzhydrylammonium salts
    1954, Vol. 19, Issue 4, pp. 732–743 [Abstract]
  • J. O. Jílek, V. Šimák and M. Protiva
    Syntheses in the estrogenic hormone group. II. Synthesis of crystalline ethyl 2-methyl-2-carbethoxy-5-(4-methoxyphenyl)cyclohexan-1-one-6-acetate
    1954, Vol. 19, Issue 2, pp. 333–339 [Abstract]
  • O. Exner, V. Šimák, J. O. Jílek and M. Protiva
    Syntheses in the estrogenic hormone group. I. m-Methoxyphenylacetylene
    1954, Vol. 19, Issue 2, pp. 330–332 [Abstract]
  • J. O. Jílek, M. Borovička and M. Protiva
    Synthetic antispasmodics. V. Cyclic analogues of substances of the 3,3-diphenylpropylamine series
    1953, Vol. 18, Issue 2, pp. 257–269 [Abstract]
  • M. Protiva, Z. J. Vejdělek and J. O. Jílek
    Synthetic antispasmodics. III. Derivatives of indane-1-carboxylic acid, 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid and indane-1-acetic acid
    1951, Vol. 16, pp. 331–343 [Abstract]
  • M. Protiva and J. O. Jílek
    Basic benzhydryl ketones. II.
    1951, Vol. 16, pp. 151–157 [Abstract]
  • J. O. Jílek and M. Protiva
    Synthesis of a new histamine analogue 2-(2'-aminoethyl)-dihydroglyoxaline
    1950, Vol. 15, pp. 659–670 [Abstract]
  • M. Protiva, V. Řeřicha, M. Borovička and J. O. Jílek
    Antihistamine substances. XVII. Some derivatives of 1-phenylindane, 1-phenyl-1,2,3,4-tetrahydronaphthalene and 2-phenyl-1,2,3,4-tetrahydroquinoline
    1950, Vol. 15, pp. 532–540 [Abstract]