Collect. Czech. Chem. Commun.
1980, 45, 1401-1409
https://doi.org/10.1135/cccc19801401
Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3
Individual author index pages
Other CCCC articles of these authors
- Václav Kozmík, Bedřich Košata, Jiří Svoboda* and Miroslav Kuchař
A Study of 5-Nitroindole Alkylation
2006, Vol. 71, Issue 5, pp. 679–690 [Abstract] - Miroslav Kuchař*, Bohumila Brunová, Richard Junek, Robert Rodling, Josef Hájíček, Vladimíra Panajotová and Antonín Jandera
The Antileukotrienic Derivatives and Homologues of [(Quinolin-2-ylmethoxy)sulfanyl]benzoic Acids with Reduced Lipophilicity
2005, Vol. 70, Issue 9, pp. 1357–1371 [Abstract] - Miroslav Kuchař*, Vojtěch Kmoníček, Vladimíra Panajotová, Antonín Jandera, Bohumila Brunová, Richard Junek, Věra Bucharová, Jan Čejka and Dalibor Šatinský
Derivatives of (Phenylsulfanyl)benzoic Acids with Multiple Antileukotrienic Activity
2004, Vol. 69, Issue 11, pp. 2098–2120 [Abstract] - Vladimír Wsól*, Barbora Szotáková, Vendula Baliharová, Luděk Šišpera, Michal Holčapek, Lenka Kolářová, Bohumila Suchanová, Miroslav Kuchař and Lenka Skálová
The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
2004, Vol. 69, Issue 3, pp. 689–702 [Abstract] - Jiří Svoboda*, Michal Štádler, Antonín Jandera, Vladimíra Panajotová and Miroslav Kuchař
Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzothiophene-2-carboxanilides
2000, Vol. 65, Issue 7, pp. 1082–1092 [Abstract] - Miroslav Kuchař, Kateřina Čulíková, Vladimíra Panajotovová, Bohumila Brunová, Antonín Jandera and Vojtěch Kmoníček
2,4-Dihydroxyacetophenone Derivatives as Antileukotrienics with a Multiple Activity Mechanism
1998, Vol. 63, Issue 1, pp. 103–114 [Abstract] - Miroslav Kuchař, Marie Poppová, Antonín Jandera, Vladimíra Panajotovová, Hana Zůnová, Miloš Buděšínský, Hana Tomková, Alexandr Jegorov and Jan Taimr
Chiral Forms of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid (Flobufen) and Its Metabolite.Synthesis and Basic Biological Properties
1997, Vol. 62, Issue 3, pp. 498–509 [Abstract] - Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
Some Analogs of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid: Synthesis and Antiinflammatory Activity
1995, Vol. 60, Issue 6, pp. 1026–1033 [Abstract] - Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid and Its Derivatives
1994, Vol. 59, Issue 12, pp. 2705–2713 [Abstract] - Ludmila Fišnerová, Bohumila Brunová, Zuzana Kocfeldová, Jana Tíkalová, Eva Maturová and Jaroslava Grimová
Synthesis and analgetic efficiency of some oxy and oxo derivatives of 4(3H)-quinazolinone
1991, Vol. 56, Issue 11, pp. 2373–2381 [Abstract] - Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
Three-dimensional structures of substituted diphenyl sulfides
1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract] - Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
9,10-Dihydroergopeptines modified in position 6
1990, Vol. 55, Issue 3, pp. 819–832 [Abstract] - Karel Šindelář, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Martin Valchář, Marta Hrubantová and Miroslav Protiva
Open-ring models of hetero-cannabinoids: Synthesis of 2-(alkylthio)-5-(2-aminoethyl)hydroquinone derivatives
1990, Vol. 55, Issue 3, pp. 782–796 [Abstract] - Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
1990, Vol. 55, Issue 1, pp. 296–306 [Abstract] - Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
Synthesis of cyclohexylaliphatic acids and their pharmacological properties
1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Václav Rejholec and Václav Čepelák
On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids
1986, Vol. 51, Issue 11, pp. 2617–2625 [Abstract] - Jiří Jílek, Jiří Holubek, Emil Svátek, Jiří Schlanger, Josef Pomykáček and Miroslav Protiva
Highly polar potential metabolites of the neuroleptic agent oxyprothepin: Synthesis of 2-hydroxy-8-methylsulfonyl and 3-hydroxy-8-methylsulfonyl derivatives of 10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
1985, Vol. 50, Issue 2, pp. 519–537 [Abstract] - Karel Šindelář, Jiří Holubek, Jiří Schlanger, Antonín Dlabač, Martin Valchář and Miroslav Protiva
Synthesis of spiro(piperidine-4,6'-dibenz[b,e]-1,4-oxathiepin) and its 1-methyl derivative as potential antidepressant agents
1985, Vol. 50, Issue 2, pp. 503–509 [Abstract] - Václav Bártl, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Jiřina Metyšová and Miroslav Protiva
Potential antipsychotic agents: 2-Chloro- and 2-methyl-11-(2-piperazinoethoxy)-6,11-dihydrodibenzo[b,e]thiepins and some related compounds; Synthesis and pharmacology
1984, Vol. 49, Issue 11, pp. 2520–2530 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
1984, Vol. 49, Issue 1, pp. 122–136 [Abstract] - Jiří Křepelka, Vladimír Pouzar, Jiří Schlanger, Jiří Holubek, Jiří Körbl, Fedir Jančik and Rudolf Kotva
Oxidative transformations of some pyrimidine derivatives into oxazolidine derivatives
1983, Vol. 48, Issue 4, pp. 1212–1223 [Abstract] - Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
1983, Vol. 48, Issue 4, pp. 1077–1088 [Abstract] - Miroslav Protiva, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiří Schlanger, Jiří Urban and Marta Hrubantová
Reactions of 11-chloro-11-phenyl-6,11-dihydrodibenzo[b,e]-thiepin with piperidine and some further nucleophiles
1982, Vol. 47, Issue 11, pp. 3094–3113 [Abstract] - Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract] - Ludmila Fišnerová, Vlastimil Rábek and Oldřich Němeček
Esters of 1-p-chlorobenzoyl-5-methoxy-2-methyl-3-indolylacetic acid
1980, Vol. 45, Issue 3, pp. 901–905 [Abstract] - Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
1979, Vol. 44, Issue 1, pp. 183–193 [Abstract]