Collect. Czech. Chem. Commun.
1983, 48, 1597-1601
https://doi.org/10.1135/cccc19831597
Preparation of optically active 3-cyclopentyl-3-methyl-2-azetidinone
Jan Hauer and Jan Šebenda
Institute of Macromolecular Chemistry, Czechoslovak Academy of Sciences, 162 06 Prague 6
Abstract
The resolution of 2-cyclopentyl-2-cyanopropanoic acid gave its enantiomers, which by esterification and hydrogenation were transformed into (+) and (-)-methyl-(3-amino-2-cyclopentyl-2-methyl)propanoate. Their cyclization yielded both enantiomers of 3-cyclopentyl-3-methyl-2-azetidinone.
