Collect. Czech. Chem. Commun.
1987, 52, 602-608
https://doi.org/10.1135/cccc19870602
Salicylhydroxamic acid and its iron(III) complexes
Vladimír Špringera, Magdaléna Horňáčkováa, Rolf Karlíčekb and Božena Kopeckác
a Department of Pharmaceutical Production, Comenius University, 832 32 Bratislava
b Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, 501 65 Hradec Králové
c Department of Analytical Chemistry, Faculty of Pharmacy, Comenius University, 832 32 Bratislava
Abstract
The dissociation constants of salicylhydroxamic acid (H2L), pKa1 = 6.73 and pKa2 = 9.15 (20 °C, I = 1.0 (NaClO4)), and the stability constant of the FeHL2+ complex, logβ = 9.09, were determined by the potentiometric and spectrophotometric methods. The low-soluble Fe(OH)(HL)2.3 H2O complex was also isolated. The reagent can be conveniently used as an indicator for the chelometric determination of iron.
