Collect. Czech. Chem. Commun.
1987, 52, 1352-1355
https://doi.org/10.1135/cccc19871352
Synthesis of elastin-like peptides using the liquid phase method
M. E. Younes, S. Abdel Rahman and A. Hattaba
Faculty of Science, Zagazig University, Zagazig, Egypt
Abstract
Elastin-like peptides were synthesized by the liquid-phase method using poly(ethylene glycol) monomethyl ether (PEGM) (m.w. 5 000) as solubilizing support which provides an alternative possibility for conformational studies and spectroscopic measurements in solution. The following sequences were synthesized: Boc-Ala-Pro-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM.