Collect. Czech. Chem. Commun. 1993, 58, S52-S55
https://doi.org/10.1135/cccc1993s052

2'-Substituted adenosine analogues as trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH) inhibitors

Serge Van Calenbergh, Christophe Verlinde, André De Bruyn, Mia Callens, Elfride Van Den Eeckhout, Arthur Van Aerschot, Paul Michels, Fred Opperdoes, Wim Hol and Piet Herdewijn

Individual author index pages


Other CCCC articles of these authors

  • Dominiquer Askin, Inge Smits, Guy Schepers, Arthur Van Aerschot, Patrick Augustijns and Piet Herdewijn
    Synthesis of 3'- and 5'-cholesterol conjugates of oligonucleotides for improving cellular uptake
    Symposium Series 1999, Vol. 2, pp. 310–312 [Abstract]
    Published online 2016-05-08 23:33:35
  • Serge Van Calenbergh, Andreas Link, Shelly Fujikawa, Veerle Vanheusden, Denis De Keukeleire, Adriaan P. Ijzerman and Piet Herdewijn
    5'-Deoxy congeners of 9-(3-amido-3-deoxy-β-D-xylofuranosyl)-N6-cyclopentyladenine: New adenosine A1 receptor antagonists
    Symposium Series 1999, Vol. 2, pp. 273–276 [Abstract]
    Published online 2016-05-08 23:32:32
  • Karen Vastmans, Luk Kerremans, Chris Hendrix, Arthur Van Aerschot, Sylvie Pochet, Philippe Marlière and Piet Herdewijn
    Recognition of 1,5-anhydrohexitol adenine triphosphate by a DNA polymerase
    Symposium Series 1999, Vol. 2, pp. 156–160 [Abstract]
    Published online 2016-05-08 20:43:00
  • Arthur Van Aerschot, Mark Vandermeeren, Johan Geysen, Walter Luyten, Marc Miller, David Atkins, Sonia Preveral, Ester Saison-Behmoaras and Piet Herdewijn
    In vitro evaluation of hexitol nucleic acid antisense oligonucleotides
    Symposium Series 1999, Vol. 2, pp. 151–155 [Abstract]
    Published online 2016-05-08 20:42:54
  • Sergei N. Mikhailov, Boris S. Ermolinsky, Ekaterina V. Efimtseva, G. P. Moiseyev, V. L. Tunitskaya, E. E. Rusakova, S. N. Kochetkov, Oksana M. Gritsenko, Elezaveta S. Gromova, Arthur Van Aerschot and Piet Herdewijn
    Oligonucleotides containing hexapyranosyl nucleosides and disaccharide nucleosides: Synthesis, incorporation of dialdehyde groups and use as affinity reagents
    Symposium Series 1999, Vol. 2, pp. 141–144 [Abstract]
    Published online 2016-05-08 20:42:42
  • Arthur Van Aerschot, Yuris Maurinsh, Brigitte Allart, Valerie Boudou and Piet Herdewijn
    Analogues of hexitol nucleic acids: Structure function relationship of a new steric blocking agent
    Symposium Series 1999, Vol. 2, pp. 100–104 [Abstract]
    Published online 2016-05-08 20:41:57
  • Ekaterina V. Efimtseva, Andrei A. Rodionov, Georgii V. Bobkov, Boris S. Ermolinsky, Marina V. Fomitcheva, Sergey N. Mikhailov and Piet Herdewijn
    Studies on disaccharide nucleoside synthesis
    Symposium Series 1999, Vol. 2, pp. 22–26 [Abstract]
    Published online 2016-05-08 20:40:11
  • Philippe Van Rompaey, Vanheusden Veerle, Sylvie Pochet, Hélene Munier-Lehmann, Matheus Froeyen, Piet Herdewijn and Serge Van Calenbergh
    Thymidine (monophosphate) analogues as Mycobacterium tuberculosis thymidylate kinase inhibitors
    Symposium Series 2002, Vol. 5, pp. 393–395 [Abstract]
    Published online 2016-01-25 20:52:11
  • Philippe Van Rompaey, Kenneth A. Jacobson, Zhan-Guo Gao, Aishe Chen, Dov Barak, Soon-Ai Kim, Kyeong Lee, Andreas Link, Bruce T. Liang, Piet Herdewijn and Serge Van Calenbergh
    Amine-modified nucleosides as adenosine A3 neoceptor ligands
    Symposium Series 2002, Vol. 5, pp. 267–271 [Abstract]
    Published online 2016-01-25 20:41:17
  • Ekaterina V. Efimtseva, Sergey N. Mikhailov, Jef Rozenski, Roger Busson, Arthur Van Aerschot and Piet Herdewijn
    Protection of 1-methyladenosine and its chemical incorporation into oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 195–199 [Abstract]
    Published online 2016-01-25 20:40:02
  • Liesbet Cosyn, Kenneth A. Jacobson and Serge Van Calenbergh
    2-(1,2,3-Triazol-1-yl) N6-CH3-substituted adenosine derivatives: Highly potent and selective A3 receptor ligands
    Symposium Series 2005, Vol. 7, pp. 393–394 [Abstract]
    Published online 2015-11-08 11:56:11
  • Sergey N. Mikhailov, Ekaterina V. Efimtseva, Alexandra A. Shelkunova, Jef Rozenski, Gert Emmerechts, Arthur Van Aerschot and Piet Herdewijn
    Chemical incorporation of minor tRNA component O-β-D-ribofuranosyl-(1''-2')-adenosine-5''-phosphate into oligoribonucleotides
    Symposium Series 2005, Vol. 7, pp. 333–337 [Abstract]
    Published online 2015-11-08 11:54:55
  • Ineke Van Daele, Hélene Munier-Lehmann and Serge Van Calenbergh
    Exploring high affinity inhibitors of M. tuberculosis thymidiylate kinase
    Symposium Series 2005, Vol. 7, pp. 313–314 [Abstract]
    Published online 2015-11-08 11:54:32
  • Piet Herdewijn
    The Diels–Alder cyclo addition as key reaction for the synthesis of cyclohexenyl nucleosides
    Symposium Series 2005, Vol. 7, pp. 29–37 [Abstract]
    Published online 2015-11-08 11:50:03
  • Mikhail Abramov, Michael Fisher, Arthur Van Aerschot, Dong Xu, Rudolph L. Juliano and Piet Herdewijn
    Inhibition of gene expression with altritol- and hexitol-modified siRNAs
    Symposium Series 2008, Vol. 10, pp. 300–301 [Abstract]
    Published online 2015-10-30 18:39:42
  • Serge Van Calenbergh, Ineke Van Daele, Sara Van Poecke, Matheus Froeyen, Hélene Munier Lehmann and Jan Balzarini
    From M. tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitors towards mitochondrial thymidine kinase (TK-2) inhibitors
    Symposium Series 2008, Vol. 10, pp. 87–93 [Abstract]
    Published online 2015-10-30 18:35:35
  • Sara Van Poecke, Matt Barrett, Kenneth A. Jacobson, T. Kendall Harden and Serge Van Calenbergh
    Synthesis of base-substituted uridine 5'-phosphonate analogues as potential P2Y2 receptor ligands
    Symposium Series 2011, Vol. 12, pp. 485–486 [Abstract]
    Published online 2015-08-20 10:25:20
  • Kiran Toti, Jan Balzarini and Serge Van Calenbergh
    Dideoxyapiose nucleosides revisited: syntheses and protide derivatives
    Symposium Series 2011, Vol. 12, pp. 480–482 [Abstract]
    Published online 2015-08-20 10:25:10
  • Martin Kögler, Bart Vanderhoydonck, Steven de Jonghe, Jean Herman, Thierry Louat, Kristien van Belle, Jef Rozenski and Piet Herdewijn
    Synthesis and evaluation of 5-substituted-2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis
    Symposium Series 2011, Vol. 12, pp. 364–366 [Abstract]
    Published online 2015-08-20 10:19:12
  • Anastasia Parchina, Matheus Froeyen, Lia Margamuljana, Jef Rozenski, Steven de Jonghe, Yves Briers, Rob Lavigne, Piet Herdewijn and Eveline Lescrinier
    Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium Tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue
    Symposium Series 2014, Vol. 14, pp. 342–343 [Abstract]
    Published online 2015-07-06 23:07:34
  • Matheus Froeyen, Hans De Winter and Piet Herdewijn*
    Conformational Analysis, Solvent-Accessible Surface and Geometric Extent of Inhibitors and Substrates
    2006, Vol. 71, Issue 6, pp. 842–858 [Abstract]
  • Georgii V. Bobkov, Kirill V. Brilliantov, Sergey N. Mikhailov*, Jef Rozenski, Arthur Van Aerschot and Piet Herdewijn
    Synthesis of Oligoribonucleotides Containing Pyrimidine 2'-O-[(Hydroxyalkoxy)methyl]ribonucleosides
    2006, Vol. 71, Issue 6, pp. 804–819 [Abstract]
  • Ding Zhou, Irene M. Lagoja, Arthur Van Aerschot and Piet Herdewijn*
    Synthesis of Aminopropyl Phosphonate Nucleosides with Purine and Pyrimidine Bases
    2006, Vol. 71, Issue 1, pp. 15–34 [Abstract]
  • Thierry Lioux, Roger Busson, Jef Rozenski, Martine Nguyen-Distèche, Jean-Marie Frère and Piet Herdewijn*
    Synthesis of Peptidoglycan Units with UDP at the Anomeric Position
    2005, Vol. 70, Issue 10, pp. 1615–1641 [Abstract]
  • Irene M. Lagoja, Koen Nauwelaerts, Christine Bal-Mahieu, Michela Pasqualini, Christian Bailly and Piet Herdewijn*
    Synthesis and Leukemia Cell Growth Inhibition of a Series of 1,3-Dithiazolylbenzene Derivatives
    2004, Vol. 69, Issue 7, pp. 1491–1498 [Abstract]
  • Zhenyu Zhang, Arthur Van Aerschot, Patrick Chaltin, Roger Busson and Piet Herdewijn*
    Epimerization During Coupling to the Unnatural Amino Acid in Solid Phase Peptide Synthesis
    2001, Vol. 66, Issue 6, pp. 923–932 [Abstract]
  • Irene M. Lagoja, Arthur Van Aerschot, Chris Hendrix and Piet Herdewijn*
    Glycosylation of 1-Aminoimidazole-2(3H)-thiones
    2000, Vol. 65, Issue 7, pp. 1145–1155 [Abstract]
  • Sergey N. Mikhailov, Ekaterina V. Efimtseva, Boris S. Ermolinsky, Marina V. Fomitcheva, Oxana M. Gritsenko, Maxim G. Brevnov, Elizaveta S. Gromova, Guy Schepers, Arthur Van Aerschot and Piet Herdewijn
    Regioselective incorporation of reactive dialdehyde groups into synthetic oligonucleotides
    1996, Vol. 61, Special Issue, pp. S210–S212 [Abstract]
  • Ekaterina V. Efimtseva, Boris S. Ermolinsky, Marina V. Fomitcheva, Sergey V. Meshkov, Nelly Sh. Padyukova, Sergey N. Mikhailov, Arthur Van Aerschot, Jef Rozenski and Piet Herdewijn
    Synthesis of disaccharide nucleosides and their incorporation into oligonucleotides
    1996, Vol. 61, Special Issue, pp. S206–S209 [Abstract]
  • Mirella Marangoni, Arthur Van Aerschot, Patrick Augustijns and Piet A. Herdewijn
    Cyclopentylethyl nucleosides as "constrained" acyclic building blocks for oligonucleotides
    1996, Vol. 61, Special Issue, pp. S203–S205 [Abstract]
  • C. Pannecouque, K. Van Poppel, Arthur Van Aerschot and Piet Herdewijn
    Synthesis and physicochemical properties of oligonucleotides with an N-cyanoguanidine function instead of the natural phosphate internucleotide linkage
    1993, Vol. 58, Special Issue, pp. S191–S194 [Abstract]
  • Arthur Van Aerschot, F. Vandendriessche, K. Augustyns and Piet Herdewijn
    Acyclic nucleosides: Useful for antisense constructs or as universal analogues for degenerate positions?
    1993, Vol. 58, Special Issue, pp. S98–S101 [Abstract]
  • Ilse Verheggen, Nathalie Pillet, Arthur Van Aerschot, Erik De Clercq and Piet Herdewijn
    Synthesis and anti-herpesvirus activity of nucleosides with a 1,5-anhydrohexitol moiety
    1993, Vol. 58, Special Issue, pp. S64–S67 [Abstract]
  • Tadeusz Kulikowski, Jaroslaw Poznanski, Jan Balzarini, Arthur Van Aerschot and Erik De Clercq
    Synthesis, conformation and anti-HIV activity of 3'-substituted 2',3'-dideoxy-5-hydroxymethyluridines
    1993, Vol. 58, Special Issue, pp. S44–S46 [Abstract]
  • Arthur Van Aerschot, Liu Jie, Jan Balzarini, Erik De Clercq and Piet Herdewijn
    5'-O-Phosphonomethyl-2',3'-dideoxynucleosides: Synthesis and anti-HIV activity
    1990, Vol. 55, Special Issue, pp. S129–S132 [Abstract]
  • Mikko Oivanen, Tuula Viinamäki, Sergei Zavgorodny, Michael Polianski, Alex Azhayev, Arthur Van Aerschot, Piet Herdewijn and Harri Lönnberg
    Hydrolytic stability of potential antiviral nucleoside analogues: 3'-Substituted 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxyribonucleosides
    1990, Vol. 55, Special Issue, pp. S17–S20 [Abstract]
  • Piet Wigerinck, Paul Claes, Arthur Van Aerschot and Piet Herdewijn
    Heterocycles in the 5-position of 2'-deoxyuridine
    1990, Vol. 55, Special Issue, pp. S5–S8 [Abstract]