Collect. Czech. Chem. Commun. 1999, 64, 114-118
https://doi.org/10.1135/cccc19990114

Agroclavine Glycosylation

Vladimír Křen*, Petr Halada and Petr Sedmera

Institute of Microbiology, Academy of Sciences of the Czech Republic, Laboratory of Biotransformation, Vídeňská 1083, 142 20 Prague 4, Czech Republic

Abstract

Agroclavine was converted into its 1-hydroxymethyl derivative by condensation with formaldehyde and enzymatically glycosylated using β-galactosidase from Aspergillus oryzae.

Keywords: Ergot alkaloids; Glycosides; Agroclavine; β-Galactopyranosides; β-Galactosidase; Aspergillus oryzae; Enzymatic reactions; Biocatalysis.